Reversible RNA Modification N 1 -methyladenosine (m 1 A) in mRNA and tRNA
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چکیده
منابع مشابه
N6-methyladenosine Modification in Bacterial mRNA
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The combination of Reverse Transcription (RT) and high-throughput sequencing has emerged as a powerful combination to detect modified nucleotides in RNA via analysis of either abortive RT-products or of the incorporation of mismatched dNTPs into cDNA. Here we simultaneously analyze both parameters in detail with respect to the occurrence of N-1-methyladenosine (m(1)A) in the template RNA. This ...
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1 Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA 7 2 Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical 8 School, Worcester, MA 01605, USA 9 3 Donnelly Centre and Departments of Molecular Genetics and Computer Science, University of Toronto 10 and Lunenfeld-Tanenbaum Research Institute, Mt Sinai Hospital, Toronto M...
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ژورنال
عنوان ژورنال: Genomics, Proteomics & Bioinformatics
سال: 2018
ISSN: 1672-0229
DOI: 10.1016/j.gpb.2018.03.003